Dyrk1A-IN-5
Code | Size | Price |
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TAR-T61739-5mg | 5mg | £284.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T61739-50mg | 50mg | £1,187.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T61739-100mg | 100mg | £1,830.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Dyrk1A-IN-5 (compound 5j) is a highly potent and selective inhibitor of DYRK1A, exhibiting an IC50 of 6 nM. It dose-dependently diminishes the phosphorylation of Thr434 in SF3B1, with an IC50 of 0.5 uM. Moreover, Dyrk1A-IN-5 effectively inhibits the phosphorylation of tau at Thr212, with an IC50 of 2.1 uM. Given these properties, Dyrk1A-IN-5 is a valuable tool for Down syndrome research [1].
CAS:
1685235-41-9
Molecular Weight:
388.164
Purity:
0.98
SMILES:
OC(=O)c1nc2ccccc2c2[nH]c3c(I)cccc3c12