HDAC-IN-46
Code | Size | Price |
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TAR-T62514-5mg | 5mg | £1,167.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62514-50mg | 50mg | £2,307.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62514-100mg | 100mg | £2,898.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.21 uM) and HDAC6 (IC50: 0.021 uM). HDAC-IN-46 upregulates p-p38 and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 can block the cell cycle in G2 phase and induce apoptosis. HDAC-IN-46 can be used in triple negative breast cancer (TNBC) studies.
CAS:
2562386-85-8
Molecular Weight:
438.536
Purity:
0.98
SMILES:
CCc1nc(N)nc(N)c1-c1ccc(cc1)-c1cn(CCCCCCCC(=O)NO)nn1