Tau-aggregation and neuroinflammation-IN-1
Code | Size | Price |
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TAR-T62899-5mg | 5mg | £102.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62899-10mg | 10mg | £122.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62899-25mg | 25mg | £168.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62899-50mg | 50mg | £229.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62899-100mg | 100mg | £306.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflammation-IN-1 has anti-inflammatory activity and reduces NO release.Tau-aggregation and neuroinflammation-IN-1 has low cytotoxicity against LSP-stimulated BV2 cells.Tau-aggregation and neuroinflammation-IN-1 reverses okadaic acid-induced memory impairment in rats.
CAS:
2175953-98-5
Molecular Weight:
460.44
Pathway:
Immunology/Inflammation|Cytoskeletal Signaling
Purity:
0.98
SMILES:
C[C@@]12C=3C(OC1=CC4=C(C2=O)C(C)=NN4C5=CC=C(C(O)=O)C=C5)=C(C(C)=O)C(O)=C(C)C3O
Target:
NO Synthase|Microtubule Associated
References
Shi CJ, et al. Usnic acid derivatives as tau-aggregation and neuroinflammation inhibitors. Eur J Med Chem. 2020 Feb 1;187:111961.