KRAS inhibitor-17
Code | Size | Price |
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TAR-T62981-5mg | 5mg | £1,167.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62981-50mg | 50mg | £2,307.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T62981-100mg | 100mg | £2,898.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
KRAS inhibitor-17 (compound 3-9) is a potent inhibitor of KRAS G12C (IC50: 3.37 uM). KRAS inhibitor-17 exhibits p-ERK inhibition with IC50 = 9.25 uM in MIA PaCA-2 cells and >33.3 uM in A549 cells. KRAS inhibitor-17 has the potential to be studied in pancreatic, colorectal and lung cancers.
CAS:
2230873-65-9
Molecular Weight:
466.35
Purity:
0.98
SMILES:
COc1ccc(Cl)c(c1)-c1c(Cl)cc2c(snc2c1F)N1CCN(CC1)C(=O)C=C