SB-284851-BT
Code | Size | Price |
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TAR-T69815-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T69815-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T69815-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
SB-284851-BT is an inhibitor of BRD4/p38α/BRDT . SB-284851-BT inhibits BRD4-BD1 ( IC 50 =1.7 uM), p38α ( K d =0.47 nM), BRDT (1) ( IC 50 = 18 uM) and BRD4 (1)( IC 50 =3.7 uM). SB-284851-BT reduces IL-8 production by inhibiting p38α , as well as inhibiting BRD4 to down-regulates c-Myc and NF-κB gene pathways in cancer . SB-284851-BT can combined with the bromine domain and extra terminal (BET) .
CAS:
219769-23-0
Molecular Weight:
443.52
Purity:
0.98
SMILES:
FC1=CC=C(C=C1)C=2N=CN(C2C=3N=C(N=CC3)OC=4C=C(C=C(C4)C)C)C5CCNCC5