Clofibric Acid-d4

TargetMol
Product Code: TAR-T71305
Supplier: TargetMol
CodeSizePrice
TAR-T71305-5mg5mg£850.00
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Quantity:
TAR-T71305-50mg50mg£1,661.00
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Quantity:
TAR-T71305-100mg100mg£2,079.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 uM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 ug/L. Clofibric acid has been found in wastewater effluent.
CAS:
1184991-14-7
Molecular Weight:
218.6694
Purity:
0.98