CIA-1 hcl(452087-38-6 Free base)
Code | Size | Price |
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TAR-T71534-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T71534-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T71534-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 uM to 7.6 uM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.
CAS:
1049691-47-5
Molecular Weight:
365.88
Pathway:
Neuroscience|Stem Cells|Proteases/Proteasome
Purity:
0.98
SMILES:
Cl.N=1C=NC(NCCC2=CC=C(OC)C(OC)=C2)=C3C=C(SC13)C
Target:
Gamma-secretase
References
Matsumoto T, et al. Characterization of CIA-1, an Ambler class A extended-spectrum ?-lactamase from Chryseobacterium indologenes. Antimicrob Agents Chemother. 2012;56(1):588-590.
Renshaw RW, et al. A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture. J Virol. 1996;70(12):8872-8878.