PD-1/PD-L1-IN-29

TargetMol
Product Code: TAR-T72721
Supplier: TargetMol
CodeSizePrice
TAR-T72721-5mg5mg£631.00
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Quantity:
TAR-T72721-50mg50mg£1,661.00
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Quantity:
TAR-T72721-100mg100mg£2,079.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC 50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity .
CAS:
2665734-13-2
Molecular Weight:
460.48
Purity:
0.98
SMILES:
O=C1N(C(=O)C=2C1=CC(CN[C@H](C(O)=O)CO)=C(OC)C2)C3=C(C)C(=CC=C3)C4=CC=CC=C4