GEM-5
Code | Size | Price |
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TAR-T74530-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T74530-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
GEM-5 is a gemcitabine-based conjugate containing a HIF-1α inhibitor (YC-1) ( IC 50 =30 nM). GEM-5 can significantly down-regulate the expression of HIF-1α and up-regulate the expression of tumor suppressor p53 . GEM-5 induces the apoptosis of A2780 cells and inhibits tumor growth [1] .
CAS:
2233543-49-0
Molecular Weight:
649.6
Purity:
0.98