NU223612
Code | Size | Price |
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TAR-T74992-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T74992-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
NU223612 is a potent PROTAC ( PROTACs ) that degrades indoleamine 2,3-dioxygenase 1 (IDO1) ( Indoleamine 2,3-Dioxygenase (IDO) ) with a K d of 640 nM. NU223612 potently degrades the IDO1 protein through CRBN -mediated proteasomal degradation. NU223612 is bound to CRBN with an affinity of 290 nM. NU223612 can cross the blood-brain barrier (BBB) [1] .
CAS:
2759420-43-2
Molecular Weight:
890.99
Purity:
0.98