Teprotumumab

TargetMol
Product Code: TAR-T76727
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T76727-50mg50mgEnquire
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TAR-T76727-5mg5mgEnquire
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Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Further Information

Bioactivity:
Teprotumumab is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R . Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research [1] .
CAS:
1036734-93-6
Purity:
0.98