Cendakimab

TargetMol
Product Code: TAR-T76942
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T76942-50mg50mgEnquire
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TAR-T76942-5mg5mgEnquire
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Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Further Information

Bioactivity:
Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC 50 s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) [1] .
CAS:
2151032-62-9
Purity:
0.98