TargetMol

JAK3/BTK-IN-2

Product Code:
 
TAR-T9813
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T9813-5mg5mg£430.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T9813-10mg10mg£613.00
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Quantity:
TAR-T9813-25mg25mg£997.00
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Quantity:
TAR-T9813-50mg50mg£1,458.00
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Quantity:
TAR-T9813-100mg100mg£2,155.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor. JAK3/ BTk-in-2 inhibits both BTK and JAK3, which are two important targets IN autoimmune diseases. JAK3/ BTk-in-2 simultaneously inhibits the BTK/JAK3 signaling pathway, showing a synergistic effect. JAK3/ BTk-in-2 has the potential to treat diseases associated with abnormal JAK3 and BTK activity.
CAS:
2674036-93-0
Molecular Weight:
476.57
Pathway:
Tyrosine Kinase/Adaptors|Angiogenesis|JAK/STAT signaling|Stem Cells|Chromatin/Epigenetic
Purity:
0.98
SMILES:
N(C1=C2C(=CNC2=NC(NC3=CN(N=C3)C4CCOCC4)=N1)C5CC5)[C@H]6CN(C(C=C)=O)CCC6
Target:
BTK|JAK

References

Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1.