KRAS G12C inhibitor 14
Code | Size | Price |
---|
TAR-T11768-10mg | 10mg | £838.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T11768-25mg | 25mg | £1,589.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].
CAS:
2349393-95-7
Formula:
C24H19ClF2N4O3
Molecular Weight:
484.88
Pathway:
GPCR/G Protein|MAPK
Purity:
0.98
SMILES:
FC1=CC=CC(O)=[C@@]1[C@@]2=C(F)C(N=CC(N3C)=C4N5[C@H](CN(C(C=C)=O)CC5)C3=O)=C4C=C2Cl
Target:
Ras
References
Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.