TargetMol

2-(Chloromethyl)-4-(4-nitrophenyl)thiazole

Product Code:
 
TAR-T2S0837
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T2S0837-10mg10mg£104.00
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TAR-T2S0837-25mg25mg£120.00
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TAR-T2S0837-50mg50mg£139.00
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TAR-T2S0837-100mg100mg£169.00
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TAR-T2S0837-500mg500mg£331.00
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Further Information

Bioactivity:
2-(Chloromethyl)-4-(4-nitrophenyl)thiazole is a natural product derived from Astragalus propinquus.2-(Chloromethyl)-4-(4-nitrophenyl)thiazole exhibits anticancer activity. 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole possesses anticancer activity and has been shown to be active in hepatocellular carcinoma (HCC) by inhibiting the M2 polarization of tumor-associated macrophages (TAM).
CAS:
89250-26-0
Molecular Weight:
254.69
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
O=N(=O)C=1C=CC(=CC1)C=2N=C(SC2)CCl
Target:
TAM Receptor

References

Zhang G, et al. Neuroprotective Effect of Astragalus Polysacharin on Streptozotocin (STZ)-Induced Diabetic Rats. Med Sci Monit. 2019;25:135-141. Li C, et al. Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages. Pharm Biol. 2021;59(1):1533-1539. Jing XN, et al. In vitro anti-tumor effect of human dendritic cells vaccine induced by astragalus polysacharin: an experimental study. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014;34(9):1103-1107.