Calpain Inhibitor XII
| Code | Size | Price |
|---|
| TAR-T21949-25mg | 25mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (u-calpain) with Ki of 19 nM. (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, K i =120 nM) and cathepsin B (K i =750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury [1].
CAS:
181769-57-3
Molecular Weight:
482.57
Purity:
0.98
SMILES:
O=C(OCC=1C=CC=CC1)NC(C(=O)NC(C(=O)C(=O)NCC2=NC=CC=C2)CCC)CC(C)C