MB710
Code | Size | Price |
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TAR-T9661-25mg | 25mg | £1,564.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T9661-50mg | 50mg | £2,464.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
MB710 is an aminobenzothiazole derivative which is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C, with a K d of 4.1 uM. MB710 shows anticancer activity in p53-Y220C cell lines [1].
CAS:
2230044-57-0
Molecular Weight:
457.29
Purity:
0.98
SMILES:
CCN(CC)c1nc2c(C(O)=O)c(O)c(I)c(-n3cccc3)c2s1