4-Aminopyridine
Code | Size | Price |
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TAR-T0817-50mg | 50mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
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Further Information
Bioactivity:
4-Aminopyridine is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.
CAS:
504-24-5
Formula:
C5H6N2
Molecular Weight:
94.1145
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Nc1ccncc1
Target:
Potassium Channel
References
Sherratt, R.M., H. Bostock, and T.A. Sears, Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres. Nature, 1980. 283(5747): p. 570-2.
Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76.