PDD00017273
Code | Size | Price |
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TAR-T5700-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T5700-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
PDD 00017273 is a potent Poly(ADP-ribose) Glycohydrolase (PARG) inhibitor with an IC 50 of 26 nM and a KD of 1.45 nM [1] [2].
CAS:
1945950-21-9
Molecular Weight:
514.62
Purity:
0.98
SMILES:
Cc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnc(C)s3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1
References
Sun Y, Chen J, Pommier Y.Real-time imaging of drug-induced trapping of cellular topoisomerases and poly (ADP-ribose) polymerase 1 at the single-molecule level.Nucleic Acids Research.2023: gkad735.