MPT0G211
Code | Size | Price |
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TAR-T60616-50mg | 50mg | £1,026.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60616-100mg | 100mg | £1,564.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
MPT0G211 is a potent, orally active and selective HDAC6 inhibitor that can penetrate the blood-brain barrier (IC50 = 0.291nM ). MPT0G211 shows >1000-fold selective for HDAC6 over other HDAC isoforms. MPT0G211 shows neuroprotective and anti-metastatic effects as well as anticancer activities. MPT0G211 improves tau phosphorylation and cognitive deficits in an Alzheimer?s disease model. [1] [2] [3].
CAS:
2151853-97-1
Molecular Weight:
293.326
Purity:
0.98
SMILES:
ONC(=O)c1ccc(CNc2cccc3cccnc23)cc1