Pentagamavunon-1
| Code | Size | Price |
|---|
| TAR-T61181-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T61181-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Pentagamavunon-1 (PGV-1) is an oral Curcumin analog that effectively induces apoptosis through multiple molecular mechanisms. It primarily targets and inhibits key angiogenic factors, including cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF), which play crucial roles in mediating cell proliferation and survival. Additionally, PGV-1 possesses the ability to inhibit the activation of NF-κB, further enhancing its apoptotic effects. [1]
CAS:
27060-70-4
Formula:
C23H24O3
Molecular Weight:
348.442
Purity:
0.98
SMILES:
Cc1cc(C=C2CCC(=Cc3cc(C)c(O)c(C)c3)C2=O)cc(C)c1O