TM-1
Code | Size | Price |
---|
TAR-T63012-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T63012-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 uM) and PDHK2 (IC50: 5.2 uM). TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits cancer cell proliferation.
CAS:
921099-13-0
Molecular Weight:
468.55
Purity:
0.98
SMILES:
O=C1OC2=CC(OCCN3CCN(CCO)CC3)=CC=C2C(=C1C=4C=CC(OC)=C(OC)C4)C