NF-κB/MAPK-IN-1
Code | Size | Price |
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TAR-T63119-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T63119-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
NF-κB/MAPK-IN-1 (compound 11a) is a potent inhibitor of NF-κB and MAPK pathways. NF-κB/MAPK-IN-1 could inhibit the production of NO (IC50: 6.96 uM). NF-κB/MAPK-IN-1 inhibited LPS-induced activation of iNOS, COX-2, ER-κ and P38, and inhibited LPS-induced inflammatory response in macrophages. NF-κB/MAPK-IN-1 can be used to study rheumatoid arthritis (RA).
CAS:
2413940-56-2
Molecular Weight:
477.513
Purity:
0.98
SMILES:
COc1ccc(C(C)=O)c(Oc2ccc(NC(=O)\C=C\c3cc(OC)c(OC)c(OC)c3)cc2)c1