Sitagliptin phosphate monohydrate
Code | Size | Price |
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TAR-T0242L-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0242L-100mg | 100mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Sitagliptin phosphate is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.
CAS:
654671-77-9
Formula:
C16H15F6N5O?H3PO4?H2O
Molecular Weight:
523.32
Pathway:
Proteases/Proteasome|Autophagy|Ubiquitination
Purity:
0.9965
SMILES:
C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O
Target:
DPP-4|Autophagy|Proteasome
References
Kim SJ et al. Diabetes. 2009; 58(3): 641-651.
Thomas L et al. J Pharmacol Exp Ther. 2008; 325(1): 175-182.