BPN-15606 besylate (1914989-49-3 free base)
Code | Size | Price |
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TAR-T10589-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T10589-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
CAS:
T10589
Formula:
C29H29FN6O4S
Molecular Weight:
576.64
Purity:
0.98
SMILES:
O=S(C1=CC=CC=C1)(O)=O.CC2=CC(C3=NC(OC)=C(N4C=C(C)N=C4)C=C3)=NN=C2N[C@H](C5=CC=C(F)C=C5)C
References
Wagner SL, et al. Pharmacological and Toxicological Properties of the Potent Oral ?-Secretase Modulator BPN-15606. J Pharmacol Exp Ther. 2017 Jul;362(1):31-44.