TargetMol

Calcium 2-oxoglutarate

Product Code:
 
TAR-T10664
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T10664-100mg100mgEnquire
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TAR-T10664-500mg500mgEnquire
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Further Information

Bioactivity:
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
CAS:
71686-01-6
Formula:
C5H8CaO5
Molecular Weight:
188.192
Pathway:
Others|Proteases/Proteasome
Purity:
0.98
SMILES:
[CaH2].OC(=O)CCC(=O)C(O)=O
Target:
Others|Tyrosinase

References

Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662. Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35.