Cetirizine D4

TargetMol
Product Code: TAR-T10769
Supplier: TargetMol
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TAR-T10769-100mg100mgEnquire
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TAR-T10769-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Cetirizine D4 is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
CAS:
1219803-84-5
Formula:
C21H25ClN2O3
Molecular Weight:
392.91
Pathway:
Immunology/Inflammation|Neuroscience|GPCR/G Protein
Purity:
0.98
SMILES:
C(N1CCN(C(C(OCC(O)=O)([2H])[2H])([2H])[2H])CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3
Target:
Histamine Receptor

References

Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055?1080, 1993.