TargetMol

Duocarmycin GA

Product Code:
 
TAR-T11115
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T11115-100mg100mgEnquire
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TAR-T11115-500mg500mgEnquire
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Further Information

Bioactivity:
Duocarmycin GA can be used against multi-drug resistant cell lines. Duocarmycin GA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove.
CAS:
1613286-59-1
Formula:
C26H25ClN4O3
Molecular Weight:
476.96
Purity:
0.98
SMILES:
C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC=C(NC(CN(C)C)=O)C4)C1)C=C(O)C=5C2=CC=CC5

References

Searcey M. Duocarmycins--natures prodrugs? Curr Pharm Des. 2002;8(15):1375-89.