Gamma-glutamylcysteine TFA
| Code | Size | Price |
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| TAR-T11357-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T11357-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes. Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx).
CAS:
283159-88-6
Formula:
C10H15F3N2O7S
Molecular Weight:
364.29
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
OC(=O)C(F)(F)F.N[C@@H](CCC(=O)N[C@H](CS)C(O)=O)C(O)=O
Target:
IL Receptor
References
Braidy N, et al. The Precursor to Glutathione (GSH), ?-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by A?40 Oligomers in Human Astrocytes. Front Aging Neurosci. 2019 Aug 8;11:177.