TargetMol

GNF179 (Metabolite)

Product Code:
 
TAR-T11445
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
GNF179 metabolite is the metabolite of GNF179, which is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
CAS:
1310455-86-7
Formula:
C14H16FN3
Molecular Weight:
245.3
Purity:
0.98
SMILES:
FC=1C=CC(=CC1)C=2N=C3N(C2)CCNC3(C)C

References

Meister S, et al. Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science. 2011 Dec 9;334(6061):1372-7.