TargetMol

Lansoprazole Sulfide D4

Product Code:
 
TAR-T11817
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 uM intracellularly and 0.46 uM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.
CAS:
1216682-38-0
Formula:
C16H14F3N3OS
Molecular Weight:
357.39
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
S(CC1=C(C)C(OCC(F)(F)F)=CC=N1)C=2NC=3C(N2)=C(C(=C(C3[2H])[2H])[2H])[2H]
Target:
Proton pump

References

Mdanda S, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12).