TargetMol

LIT-001 free base

Product Code:
 
TAR-T11856
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T11856-100mg100mgEnquire
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TAR-T11856-500mg500mgEnquire
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Further Information

Bioactivity:
LIT-001 free base improves social interaction in a mouse model of autism. LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM).
CAS:
2245072-20-0
Formula:
C28H33N7O2S
Molecular Weight:
531.67
Purity:
0.98
SMILES:
C(=O)(N1C=2C(NC3=C(C1)C=NN3C)=CC=CC2)C4=CC(C)=C(CNC(=O)N5[C@H](C(N(C)C)=S)CCC5)C=C4

References

Frantz MC, et al. LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism. J Med Chem. 2018 Oct 11;61(19):8670-8692.