Propranolol-d7 hydrochloride

TargetMol
Product Code: TAR-T12550
Supplier: TargetMol
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Propranolol D7 hydrochloride is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective antagonist of β-adrenergic receptor (βAR).
CAS:
1613439-56-7
Formula:
C16H22ClNO2
Molecular Weight:
302.85
Purity:
0.98
SMILES:
O(CC(CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])O)C=1C2=C(C=CC1)C=CC=C2.Cl

References

Briley M, et al. Evidence against beta-adrenoceptor blocking activity of diltiazem, a drug with calcium antagonist properties. Br J Pharmacol. 1980 Aug;69(4):669-73. Al-Majed AA, et al. Propranolol. Profiles Drug Subst Excip Relat Methodol. 2017;42:287-338. Galandrin S, et al. Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy. Mol Pharmacol. 2006 Nov;70(5):1575-84.