TargetMol

Thalidomide D4

Product Code:
 
TAR-T13141
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T13141-100mg100mgEnquire
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TAR-T13141-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.
CAS:
1219177-18-0
Formula:
C13H10N2O4
Molecular Weight:
262.25
Purity:
0.98
SMILES:
O=C1N(C(=O)C=2C1=C(C(=C(C2[2H])[2H])[2H])[2H])C3C(=O)NC(=O)CC3

References

Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53. Sun X, et al. Synergistic Inhibition of Thalidomide and Icotinib on Human Non-Small Cell Lung Carcinomas Through ERK and AKT Signaling. Med Sci Monit. 2018 May 15;24:3193-3203.