AT6

TargetMol
Product Code: TAR-T13561
Supplier: TargetMol
CodeSizePrice
TAR-T13561-100mg100mgEnquire
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TAR-T13561-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
AT6 is a PROTAC AT1 analog which is a highly selective bromodomain (Brd4) degrader.
CAS:
2098836-50-9
Formula:
C48H58ClN9O7S3
Molecular Weight:
1004.68
Purity:
0.98
SMILES:
CC=1C2=C(N3C([C@H](CC(NCCOCCOCCSC([C@@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)NC(C)=O)(C)C)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C

References

Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.