TargetMol

Curvularin

Product Code:
 
TAR-T13628
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Curvulin, naturally isolated from Campylobacter curvulans, is a fungal metabolite and a potent mycotoxin that inhibits cytokine-induced nitric oxide synthase (iNOS) with IC50 of 9.5 uM.
CAS:
10140-70-2
Formula:
C16H20O5
Molecular Weight:
292.33
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
O=C(O[C@@H](C)CCCCC1)CC2=CC(O)=CC(O)=C2C1=O
Target:
NOS

References

Kumar CG, et al. Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India. Springerplus. 2013 Dec;2(1):122. Yao Y, et al. Sporogen, S14-95, and S-curvularin, three inhibitors of human inducible nitric-oxide synthase expression isolated from fungi. Mol Pharmacol. 2003 Feb;63(2):383-91.