Bromo-PEG5-phosphonic acid diethyl ester
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Bromo-PEG5-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker for PROTAC synthesis[1]. It is utilized in the construction of PROteolysis TArgeting Chimeras (PROTACs), which are heterobifunctional molecules designed to induce protein degradation.
CAS:
1446282-41-2
Formula:
C16H34BrO8P
Molecular Weight:
465.31
Purity:
0.98
SMILES:
O=P(OCC)(OCC)CCOCCOCCOCCOCCOCCBr
References
An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562