DBCO-NHCO-PEG4-NHS ester
Code | Size | Price |
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TAR-T15064-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T15064-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
CAS:
2100306-58-7
Formula:
C34H39N3O10
Molecular Weight:
649.69
Purity:
0.98
SMILES:
O=C(ON1C(=O)CCC1=O)CCOCCOCCOCCOCCC(=O)NCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2
References
Thornlow DN, et al. Dual Site-Specific Antibody Conjugates for Sequential and Orthogonal Cargo Release. Bioconjug Chem. 2019 Jun 19;30(6):1702-1710.