Fmoc-NH-ethyl-SS-propionic NHS ester
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TAR-T15312-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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TAR-T15312-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable linker for antibody-drug conjugates (ADCs)[1]. It is employed in the synthesis of ADCs, facilitating the covalent attachment of drugs to antibodies through the formation of stable amide bonds.
CAS:
2128735-23-7
Formula:
C24H24N2O6S2
Molecular Weight:
500.59
Purity:
0.98
SMILES:
O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NCCSSCCC(=O)ON4C(=O)CCC4=O
References
Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.