Fmoc-PEG3-C2-NHS ester
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based linker derived from fluorenylmethoxycarbonyl (Fmoc), which is used as a moiety for the efficient synthesis of PROTACs (proteolysis-targeting chimeras)[1]. This compound offers a practical solution for connecting desired molecules and targeting specific proteins for degradation.
CAS:
1352827-47-4
Formula:
C28H32N2O9
Molecular Weight:
540.56
Purity:
0.98
SMILES:
O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NCCOCCOCCOCCC(=O)ON4C(=O)CCC4=O
References
An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562