Mal-PEG4-Val-Cit-PAB-PNP

TargetMol
Product Code: TAR-T15995
Supplier: TargetMol
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
CAS:
2112738-09-5
Formula:
C40H53N7O15
Molecular Weight:
871.89
Purity:
0.98
SMILES:
[C@H](C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)=O)(NC([C@@H](NC(CCOCCOCCOCCOCCN3C(=O)C=CC3=O)=O)[C@H](C)C)=O)CCCNC(N)=O

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.