N-Bromoacetyl-β-alanine
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| TAR-T16222-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
N-Bromoacetyl-β-alanine is an alkyl chain-derived PROTAC linker utilized for synthesizing PROTACs[1]. Moreover, it serves as a cleavable ADC linker in the production of antibody-drug conjugates (ADCs)[2].
CAS:
89520-11-6
Formula:
C5H8BrNO3
Molecular Weight:
210.03
Purity:
0.98
SMILES:
O=C(O)CCNC(=O)CBr
References
An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.