N3-PEG3-CH2CH2-Boc
| Code | Size | Price |
|---|
| TAR-T16257-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T16257-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit polyethylene glycol (PEG) ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also functions as a PEG- and alkyl/ether-based PROteolysis TArgeting Chimera (PROTAC) linker, suitable for the construction of PROTAC molecules[2].
CAS:
252881-73-5
Formula:
C13H25N3O5
Molecular Weight:
303.35
Purity:
0.98
SMILES:
[N-]=[N+]=NCCOCCOCCOCCC(=O)OC(C)(C)C
References
Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor ? (ERR?) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.
Yongxin Robert ZHAO, et al. Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers. WO2018086139A1.