Boc-Val-Ala-PAB-PNP

TargetMol
Product Code: TAR-T17690
Supplier: TargetMol
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TAR-T17690-100mg100mgEnquire
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TAR-T17690-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Boc-Val-Ala-PAB-PNP is an ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1]. This cleavable compound efficiently facilitates the attachment of drugs to antibodies, allowing for targeted delivery and release of therapeutic agents within the body, making it an important component in ADC development.
CAS:
1884578-00-0
Molecular Weight:
558.58
Purity:
0.98
SMILES:
O(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)C(C)C)=O)C)=O)C=C1)=O)C2=CC=C(N(=O)=O)C=C2

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.