DBCO-Val-Cit-PABC-OH

TargetMol
Product Code: TAR-T17815
Supplier: TargetMol
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TAR-T17815-100mg100mgEnquire
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TAR-T17815-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
DBCO-Val-Cit-PABC-OH is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].
CAS:
T17815
Molecular Weight:
694.82
Purity:
0.98
SMILES:
O=C(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)CCCCC(N[C@@H](C(N[C@H](C(NC4=CC=C(C=C4)CO)=O)CCCNC(N)=O)=O)C(C)C)=O

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.