m-PEG8-ethoxycarbonyl-NHS ester
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
m-PEG8-ethoxycarbonyl-NHS ester is a polyethylene glycol (PEG)-based linker, utilized for the synthesis of PROTACs. It serves as an effective coupling agent, facilitating the conjugation of two molecules within PROTACs. This compound offers a stable and efficient platform for the delivery of targeted protein degradation therapeutics. [1]
CAS:
2353409-76-2
Molecular Weight:
581.61
Purity:
0.98
SMILES:
O=C(ON1C(=O)CCC1=O)CCC(=O)OCCOCCOCCOCCOCCOCCOCCOCCOC
References
An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562