MC-Val-Cit-PAB-Indibulin
Code | Size | Price |
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TAR-T18325-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T18325-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
MC-Val-Cit-PAB-Indibulin is a drug-linker conjugate for ADC with potent antitumor activity by using Indibulin (an orally applicable inhibitor of tubulin assembly), linked via the ADC linker MC-Val-Cit-PAB.
CAS:
2055896-95-0
Molecular Weight:
945.48
Purity:
0.98
SMILES:
C(C(NC=1C=C[N+](CC2=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN3C(=O)C=CC3=O)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C2)=CC1)=O)(=O)C=4C=5C(N(CC6=CC=C(Cl)C=C6)C4)=CC=CC5
References
Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.