MC-VC(S)-PABQ-Tubulysin M
Code | Size | Price |
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TAR-T18329-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T18329-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
MC-Val-Cit-PAB-tubulysin5a is a drug-linker conjugate for ADC with potent antitumor activity by using tubulysin5a (a tubulin inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
CAS:
2055896-86-9
Molecular Weight:
1283.6
Purity:
0.98
SMILES:
C(N[C@H](C(N([C@H](C[C@@H](OC(C)=O)C1=NC(C(N[C@@H](CC2=CC=CC=C2)C[C@@H](C(O)=O)C)=O)=CS1)C(C)C)C)=O)[C@H](CC)C)(=O)[C@@H]3[N+](CC4=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN5C(=O)C=CC5=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C4)(C)CCCC3
References
Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.