Methyltetrazine-PEG4-oxyamine
| Code | Size | Price |
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| TAR-T18350-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T18350-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Methyltetrazine-PEG4-oxyamine is a 4-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs), which are extensively used for targeted drug delivery [1]. This cleavable linker offers a means to efficiently attach drugs to antibodies and facilitate their controlled release at the target site.
CAS:
T18350
Molecular Weight:
521.57
Purity:
0.98
SMILES:
CC1=NN=C(C2=CC=C(CNC(CCOCCOCCOCCOCCNC(CON)=O)=O)C=C2)N=N1
References
Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.