N-(5-Hydroxypentyl)maleimide
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs). It serves as a crucial component in the production of Gemcitabine-O-Si(di-iso)-O-Mc, an ADC compound [1].
CAS:
180608-78-0
Formula:
C9H13NO3
Molecular Weight:
183.2
Purity:
0.98
SMILES:
O=C1C=CC(=O)N1CCCCCO
References
Finniss, M. C., et al. A versatile acid-labile linker for antibody?drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.